The art museum in the New York City borough of Brooklyn said it closed an hour early because of the disruption, including skirmishes between police and protesters that took place inside and outside the building.
Some arrests were made but a New York Police Department spokesperson said there would be no official count until after the protest concluded. A demonstration continued outside the museum hours after the initial confrontation, but the spokesperson could not say whether any protesters remained inside.
One of the arrests was of a man who defaced an outdoor sculpture with graffiti, a Reuters witness said. Several protesters scrawled messages on the OY/YO sculpture on the plaza outside the entrance.
"There was damage to existing and newly installed artwork on our plaza," a museum spokesperson said in an email. "Protesters entered the building, and our public safety staff were physically and verbally harassed.
Israel has killed more than 36,000 Palestinians in Gaza since a cross-border attack by Hamas on Oct. 7, which killed less than 1,200 people and around 250 were taken as hostages. As many as 105 captives were released as part of a brief truce in November in exchange for 240 Palestinian prisoners.
Around 125 people remain captive, with many believed to be dead due to Israeli airstrikes.
Indirect talks between Israel and Hamas, mediated by the US, Qatar and Egypt, have so far failed to agree on a permanent cease-fire.