A new study suggests that a combination of resveratrol and copper could significantly reduce the aggressiveness of glioblastoma, one of the deadliest forms of brain cancer, though experts caution the approach remains experimental.

Key Findings

Researchers at Mumbai’s ACTREC tested the combination in 20 patients scheduled for brain surgery. Patients who took the supplements for about 12 days before surgery showed remarkable changes in their tumors:

Tumor growth activity dropped by 33%

Cancer biomarkers decreased by 57%

Immune-checkpoint signals fell by 41%

Cancer stem-cell markers declined by 56%

No side effects were reported

The study also found a near-complete removal of harmful DNA fragments, known as cell-free chromatin particles, which fuel tumor inflammation and aggressiveness.

How It Works

Resveratrol, found in red grapes and berries, interacts with copper to produce reactive molecules that break down inflammatory DNA debris inside tumors, potentially weakening them without harming healthy tissue.

Cautions and Limitations

Researchers stressed the study involved a small patient group, short-term observations, and did not measure long-term survival. Tumor shrinkage was not observed, and interaction with standard treatments is unknown. Experts warn against self-medication.

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Conclusion

While the findings offer hope for safer, affordable glioblastoma therapy, they are not a replacement for surgery, chemotherapy, or radiotherapy. Larger, long-term trials are needed to confirm the potential of this supplement combination.